| Identification | Back Directory | [Name]
Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy- | [CAS]
142648-47-3 | [Synonyms]
Anti-Heart Failure Agent 1
Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy- | [Molecular Formula]
C11H11FN2O3S | [MDL Number]
MFCD31382017 | [MOL File]
142648-47-3.mol | [Molecular Weight]
270.28 |
| Chemical Properties | Back Directory | [Boiling point ]
413.5±55.0 °C(Predicted) | [density ]
1.50±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
6.32±0.69(Predicted) |
| Hazard Information | Back Directory | [Uses]
Anti-Heart Failure Agent 1 an orally available compound suitable for the treatment of heart failure without inducing nausea, vomiting and restlessness. | [in vivo]
15 mg/kg of compound produces 60% increase in left ventricular contractility in anaesthetized cat. An oral dose of compound (25 mg/kg) could produce marked increases in left ventricular contractility (45%) in conscious dog[1]. | [References]
[1] EP0482717A1 |
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