| Identification | Back Directory | [Name]
BMS 180680 | [CAS]
142654-34-0 | [Synonyms]
SQ 84
SQ 84,100
BMS 180680
2-Quinoxalinecarboxylic acid, 3-[[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(2R,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]methyl]-6,7-dihydroxy- | [Molecular Formula]
C19H17N7O10S2 | [MDL Number]
MFCD00912548 | [MOL File]
142654-34-0.mol | [Molecular Weight]
567.51 |
| Hazard Information | Back Directory | [Uses]
BMS-180680 (PA-1806) is an antibiotic, which exhibits a board-spectrum antibacterial activity against gram-negative bacteria. BMS-180680 inihibits Pseudomonas aeruginosa with MIC of 0.25 μg/ml. BMS-180680 exhibits resistance to hydrolysis by β-lactamases, such as TEM-2 and PSE enzymes[1]. | [References]
[1] Fung-Tomc J, et al., Antibacterial activity of BMS-180680, a new catechol-containing monobactam. Antimicrob Agents Chemother. 1997 May;41(5):1010-6. DOI:10.1128/AAC.41.5.1010 |
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