ChemicalBook--->CAS DataBase List--->1426543-84-1

1426543-84-1

1426543-84-1 Structure

1426543-84-1 Structure
IdentificationBack Directory
[Name]

GSK1521498
[CAS]

1426543-84-1
[Synonyms]

GSK-1521498,GSK1521498
[Molecular Formula]

C24H23F2N4O4P
[MDL Number]

MFCD32201816
[MOL File]

1426543-84-1.mol
[Molecular Weight]

500.44
Hazard InformationBack Directory
[Uses]

GSK1521498 is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 has the potential for disorders of compulsive consumption of food, alcohol, and agents[1].
[IC 50]

μ Opioid Receptor/MOR
[References]

[1] Giuliano C, et al. The Novel μ-Opioid Receptor Antagonist GSK1521498 Decreases Both Alcohol Seeking and Drinking: Evidence from a New Preclinical Model of Alcohol Seeking. Neuropsychopharmacology. 2015 Dec;40(13):2981-92. DOI:10.1038/npp.2015.152
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