| Identification | Back Directory | [Name]
HBX 19818 | [CAS]
1426944-49-1 | [Synonyms]
HBX 19818
HBX19818; HBX-19818
N-[3-[benzyl(methyl)amino]propyl]-9-chloro-5,6,7,8-tetrahydroacridine-2-carboxamide
9-Chloro-5,6,7,8-tetrahydro-N-[3-[methyl(phenylmethyl)amino]propyl]-2-acridinecarboxamide
2-Acridinecarboxamide, 9-chloro-5,6,7,8-tetrahydro-N-[3-[methyl(phenylmethyl)amino]propyl]- | [Molecular Formula]
C25H28ClN3O | [MOL File]
1426944-49-1.mol | [Molecular Weight]
421.96 |
| Chemical Properties | Back Directory | [Boiling point ]
631.2±55.0 °C(Predicted) | [density ]
1.206±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:12.5(Max Conc. mg/mL);29.62(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);0.47(Max Conc. mM)
Water:5.0(Max Conc. mg/mL);0.47(Max Conc. mM) | [form ]
Solid | [pka]
13.67±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
HBX 19818 is a specific inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 28.1 μM. | [storage]
Store at -20°C | [References]
[1] Reverdy C, et al. Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme. Chem Biol. 2012 Apr 20;19(4):467-77. DOI:10.1016/j.chembiol.2012.02.007 |
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| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
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