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1427325-40-3

1427325-40-3 Structure

1427325-40-3 Structure
IdentificationBack Directory
[Name]

[1-(3-methylbutan-2-yl)indol-3-yl]-naphthalen-1-ylmethanone
[CAS]

1427325-40-3
[Synonyms]

[1-(3-methylbutan-2-yl)indol-3-yl]-naphthalen-1-ylmethanone
(1-(3-methylbutan-2-yl)-1H-indol-3-yl)(naphthalen-1-yl)methanone
Methanone, [1-(1,2-dimethylpropyl)-1H-indol-3-yl]-1-naphthalenyl-
[Molecular Formula]

C24H23NO
[MOL File]

1427325-40-3.mol
[Molecular Weight]

341.45
Chemical PropertiesBack Directory
[Boiling point ]

518.6±23.0 °C(Predicted)
[density ]

1.10±0.1 g/cm3(Predicted)
[solubility ]

DMF: 20 mg/ml; DMSO: 10 mg/ml; Ethanol: 20 mg/ml
[form ]

A crystalline solid
Hazard InformationBack Directory
[Description]

JWH 018 is a synthetic cannabinoid (CB) that potently activates the central CB1 and peripheral CB2 receptors (Ki = 9.0 and 2.94 nM, respectively). This cannabimimetic compound has frequently been found in herbal blends. JWH 018 N-(1,2-dimethylpropyl) isomer differs from JWH 018 structurally by having a 1,2-dimethylpropyl chain, rather than a pentyl chain, extending from the indole group. The biological activities of this compound have not been characterized. This product is intended for forensic purposes.
[References]

[1] RAINER LINDIGKEIT . Spice: A never ending story?[J]. Forensic science international, 2009, 191 1: Pages 58-63. DOI: 10.1016/j.forsciint.2009.06.008
[2] N. UCHIYAMA. Identification of a cannabimimetic indole as a designer drug in a herbal product[J]. Forensic Toxicology, 2009, 27 1: 61-66. DOI: 10.1007/s11419-009-0069-y
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