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1427521-40-1

1427521-40-1 Structure

1427521-40-1 Structure
IdentificationBack Directory
[Name]

(4-ethylnaphthalen-1-yl)-[1-(5-hydroxypentyl)indol-3-yl]methanone
[CAS]

1427521-40-1
[Synonyms]

(4-ethylnaphthalen-1-yl)-[1-(5-hydroxypentyl)indol-3-yl]methanone
[Molecular Formula]

C26H27NO2
[MOL File]

1427521-40-1.mol
[Molecular Weight]

385.5
Chemical PropertiesBack Directory
[solubility ]

DMF: 15 mg/ml; DMSO: 14 mg/ml; Ethanol: 15 mg/ml
[form ]

A crystalline solid
Hazard InformationBack Directory
[Description]

JWH 210 is a potent cannabimimetic alkylindole that has been identified in extracts from herbal blends. Structurally and functionally similar alkylindoles are rapidly metabolized by the liver and secreted in the urine, with 5-carboxypentyl metabolites detected in the urine.1,2,3 JWH 210 N-(5-hydroxypentyl) metabolite is an expected metabolite of JWH 210, detectable in the serum and urine. Its biological activities have yet to be determined. This product is intended for forensic purposes.
[References]

1. Teske, J., Weller, J.P., Fieguth, A., et al. Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in human serum by liquid chromatography-tandem mass spectrometry J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 878(27),2659-2663(2010).
2. Sobolevsky, T., Prasolov, I., and Rodchenkov, G. Detection of JWH-018 metabolites in smoking mixture post-administration urine Forensic Sci. Int. 200(1-3),141-147(2010).
3. Wintermeyer, A., M?ller, I., Thevis, M., et al. In vitro phase I metabolism of the synthetic cannabimimetic JWH-018 Anal. Bioanal. Chem. 398(5),2141-2153(2010).
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