| Identification | Back Directory | [Name]
5,6-DIMETHYL-1-BETA-D-RIBOFURANOSYLBENZIMIDAZOLE-3',5'-CYCLIC MONOPHOSPHATE,SODIUM SALT | [CAS]
142754-31-2 | [Synonyms]
5,6-DM-cBIMP
5,6-DM-CBIMP SODIUM SALT
5,6-dimethylbenzimidazoleriboside-3’,5’-monophosphate(5,6-dm-cbimp),
1-(5,6-dimethyl-benzoimidazol-1-yl)-O3,O5-hydroxyphosphoryl-D-1,4-anhydro-ribitol
5,6-DIMETHYL-1-BETA-D-RIBOFURANOSYLBENZIMIDAZOLE-3',5'-CYCLIC MONOPHOSPHATE,SODIUM SALT | [Molecular Formula]
C14H16N2NaO6P | [MDL Number]
MFCD04118036 | [MOL File]
142754-31-2.mol | [Molecular Weight]
362.25 |
| Hazard Information | Back Directory | [Uses]
5,6-DM-cBIMP, a cyclic nucleotide analog, is an agonist of PDE2 that can significantly enhance the cAMP and cGMP hydrolytic activities of PDE2[1][2. | [References]
[1] Nakashima K, et al. A Novel Inhibition Modality for Phosphodiesterase 2A[J]. SLAS DISCOVERY: Advancing the Science of Drug Discovery, 2020, 25(5): 498-505. DOI:10.1177/2472555220913241
[2] J?ger R, et al. Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5[J]. British journal of pharmacology, 2010, 161(7): 1645-1660. DOI:10.1111/j.1476-5381.2010.00977.x |
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