| Identification | Back Directory | [Name]
V-11-0711 | [CAS]
1428339-47-2 | [Synonyms]
V-11-0711
1-Azabicyclo[2.2.2]octane-3-methanol, α-phenyl-α-[2-[2-[(tetrahydro-2H-pyran-4-yl)oxy]phenyl]ethyl]-, (αR,3S)-rel- | [Molecular Formula]
C27H35NO3 | [MOL File]
1428339-47-2.mol | [Molecular Weight]
421.57 |
| Chemical Properties | Back Directory | [Boiling point ]
558.8±50.0 °C(Predicted) | [density ]
1.18±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
13.98±0.29(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
V-11-0711 is a potent and selective choline kinase alpha (ChoKα) inhibitor with an IC50 of 20 nM. V-11-0711 causes a reversible growth arrest in HeLa cells[1]. | [References]
[1] SC Falcon, et al. A non-catalytic role of choline kinase alpha is important in promoting cancer cell survival. Oncogenesis. 2013;2(3):e38. DOI:10.1038/oncsis.2013.2 |
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