| Identification | Back Directory | [Name]
OXF BD 02 | [CAS]
1429129-68-9 | [Synonyms]
OXF BD 02
3-(3,5-Dimethyl-4-isoxazolyl)-5-hydroxy-±-phenyl-benzenemethanol
3-(3,5-Dimethyl-4-isoxazolyl)-5-hydroxy-α-phenyl-benzenemethanol
Benzenemethanol, 3-(3,5-dimethyl-4-isoxazolyl)-5-hydroxy-α-phenyl- | [Molecular Formula]
C18H17NO3 | [MOL File]
1429129-68-9.mol | [Molecular Weight]
295.34 |
| Chemical Properties | Back Directory | [Boiling point ]
515.4±50.0 °C(Predicted) | [density ]
1.233±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble to 100 mM in DMSO and to 10 mM in ethanol with gentle warming | [form ]
Powder | [pka]
9.26±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
3-(3,5-Dimethyl-4-isoxazolyl)-5-hydroxy-α-phenyl-benzenemethanol is bromodomain ligand acting as a selective inhibitor of the first bromodomain of BRD4. Potential applications involved decreased lifespan of lung adenocarcinoma cell lines and reduction of cell proliferation in leukemia cells. | [IC 50]
BRD4(1): 382 nM (IC50) | [storage]
Store at -20°C |
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| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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