| Identification | Back Directory | [Name]
4H-Pyrazolo[4,3-c]quinolin-4-one, 1,5-dihydro-7-(2-methoxy-3,5-dimethyl-4-pyridinyl)-1-[(3R)-tetrahydro-3-furanyl]- | [CAS]
1429509-81-8 | [Synonyms]
(R)-Irsenontrine
4H-Pyrazolo[4,3-c]quinolin-4-one, 1,5-dihydro-7-(2-methoxy-3,5-dimethyl-4-pyridinyl)-1-[(3R)-tetrahydro-3-furanyl]- | [Molecular Formula]
C22H22N4O3 | [MOL File]
1429509-81-8.mol | [Molecular Weight]
390.44 |
| Chemical Properties | Back Directory | [Boiling point ]
514.6±50.0 °C(Predicted) | [density ]
1.41±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, away from moisture and light | [form ]
Solid | [pka]
12.41±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
(R)-Irsenontrine ((R)-E2027), the R-enantiomer of Irsenontrine (HY-132821), is a potent phosphodiesterase 9 (PDE9) inhibitor with an IC50 value of 0.041 μM. (R)-Irsenontrine can be used for the research of neurological diseases[1]. | [IC 50]
PDE9: 0.041 μM (IC50) | [storage]
4°C, away from moisture and light | [References]
[1] Yoshihiko N, et, al. Pyrazoloquinoline derivative. WO2013051639A1. |
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