| Identification | Back Directory | [Name]
STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1 | [CAS]
142986-44-5 | [Synonyms]
PAMAMG1.0
pamam dendrimer, generation 1 solution
STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1
4,7,11,14,18,21-Hexaazatetracosanediamide, 95%
PAMAM dendrimer, ethylenediamine core, generation 1.0 solution
STARBURST (PAMAM) DENDRIMER, GENERATION 1, 20 WT. % SOLUTION IN METHYL ALCOHOL
PAMAM dendrimer, ethylenediamine core, generation 1.0 solution 20 wt. % in methanol
4,7,11,14,18,21-Hexaazatetracosanediamide, N1,N24-bis(2-aminoethyl)-4,21-bis[3-[(2-aminoethyl)amino]-3-oxopropyl]-11,14-bis[3-[[2-[bis[3-[(2-aminoethyl)amino]-3-oxopropyl]amino]ethyl]amino]-3-oxopropyl]-8,17-dioxo- | [Molecular Formula]
C62H128N26O12 | [MDL Number]
MFCD00192448 | [MOL File]
142986-44-5.mol | [Molecular Weight]
1429.85 |
| Chemical Properties | Back Directory | [Boiling point ]
64.7 °C | [density ]
0.82 g/mL at 25 °C | [refractive index ]
n20/D 1.362 | [Fp ]
52 °F | [storage temp. ]
2-8°C | [solubility ]
Water: Soluble | [form ]
20 wt.% in methanol | [color ]
Colorless to light yellow | [InChIKey]
QVWIZHOFYGKROL-UHFFFAOYSA-N | [SMILES]
C(NCCN)(=O)CCN(CCC(NCCN)=O)CCNC(=O)CCN(CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCN(CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCC(=O)NCCN(CCC(NCCN)=O)CCC(NCCN)=O |
| Hazard Information | Back Directory | [Uses]
Starburst 1st Generation (PAMAM G1.0) is a Polyamidoamine (HY-164657; PAMAM) dendrimer with amine termini that has been used as a drug delivery system in vitro. Starburst 1st Generation conjugated to di-n-dodecylamine and encapsulating 5-Fluorouracil (HY-90006) increase the solubility of 5-Fluorouracil and are cytotoxic to AGS gastric adenocarcinoma cells[1]. | [References]
[1] Ender Sarigul, et al. Polyamidoamine Dendron-Bearing Lipids as Drug-Delivery Excipients. Molecules. 2022 Nov 13;27(22):7817. DOI:10.3390/molecules27227817 |
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Energy Chemical Gold
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Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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