| Identification | Back Directory | [Name]
L-Arginine, L-isoleucyl-L-tyrosyl-L-prolyl-L-threonyl-L-asparaginylglycyl-L-tyrosyl-L-threonyl- | [CAS]
1431957-72-0 | [Synonyms]
IYPTNGYTR
L-Arginine, L-isoleucyl-L-tyrosyl-L-prolyl-L-threonyl-L-asparaginylglycyl-L-tyrosyl-L-threonyl- | [Molecular Formula]
C49H73N13O15 | [MDL Number]
MFCD34471461 | [MOL File]
1431957-72-0.mol | [Molecular Weight]
1084.18 |
| Hazard Information | Back Directory | [Uses]
IYPTNGYTR, a deamidation-sensitive signature peptide, is a deamidation product of Trastuzumab. IYPTNGYTR can be used to monitor in vivo Trastuzumab metabolism[1]. | [References]
[1] Bults P, et, al. LC-MS/MS-Based Monitoring of In Vivo Protein Biotransformation: Quantitative Determination of Trastuzumab and Its Deamidation Products in Human Plasma. Anal Chem. 2016 Feb 2;88(3):1871-7. DOI:10.1021/acs.analchem.5b04276 |
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