| Identification | Back Directory | [Name]
ML334 | [CAS]
1432500-66-7 | [Synonyms]
ML334
LH601A
(1S,2R)-2-[[(1S)-1-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-3,4-dihydro-2(1H)-isoquinolinyl]carbonyl]cyclohexanecarboxylic acid
(1S,2R)-2-[(1S)-1-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-carbonyl]cyclohexane-1-carboxylic acid
Cyclohexanecarboxylic acid, 2-[[(1S)-1-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-3,4-dihydro-2(1H)-isoquinolinyl]carbonyl]-, (1S,2R)- | [Molecular Formula]
C26H26N2O5 | [MDL Number]
MFCD30290156 | [MOL File]
1432500-66-7.mol | [Molecular Weight]
446.49 |
| Chemical Properties | Back Directory | [Boiling point ]
693.1±55.0 °C(Predicted) | [density ]
1.354±0.06 g/cm3(Predicted) | [storage temp. ]
Store at 4°C, stored under nitrogen | [solubility ]
DMSO: 40 mg/ml | [form ]
A solid | [pka]
4.69±0.44(Predicted) | [color ]
White to off-white | [InChIKey]
LNENLABLFGGAFF-BHIFYINESA-N | [SMILES]
N4(C(=O)c5c(cccc5)C4=O)C[C@H]1N(CCc3c1cccc3)C(=O)[C@H]2[C@H](CCCC2)C(=O)O |
| Hazard Information | Back Directory | [Uses]
ML 334 is an inhibitor of Keap1-Nrf2 interaction and affects the cytoprotective responses to oxidative and electrophilic stress. May be used in cancer treatment and attenuation. | [Definition]
ChEBI: (1S,2R)-2-[[(1S)-1-[(1,3-dioxo-2-isoindolyl)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-oxomethyl]-1-cyclohexanecarboxylic acid is a member of phthalimides. | [Biological Activity]
Primary Target
Keap1–Nrf2''Reversible: yes | [storage]
Store at -20°C |
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BOC Sciences
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https://www.bocsci.com |
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