| Identification | Back Directory | [Name]
Lascufloxacin hydrochloride | [CAS]
1433857-09-0 | [Synonyms]
KRP-AM1977Y
Lascufloxacin HCl
Lascufloxacin hydrochloride | [Molecular Formula]
C21H25ClF3N3O4 | [MOL File]
1433857-09-0.mol | [Molecular Weight]
475.89 |
| Hazard Information | Back Directory | [Uses]
Lascufloxacin (KRP-AM1977) hydrochloride is a potent antibacterial compound candidate with broad-spectrum activity against various clinical isolates. Lascufloxacin hydrochloride shows the most potent activity against Gram-positive bacteria compared to other tested quinolones. Lascufloxacin hydrochloride demonstrates incomplete cross-resistance against existing quinolone-resistant strains. Lascufloxacin hydrochloride has potent inhibitory activity against both wild-type and mutated target enzymes. | [Biological Activity]
Lascufloxacin hydrochloride has potent activity against a broad range of pathogens, including aerobic and anaerobic strains, and is able to inhibit both wild-type and mutant targets, making it effective against fluoroquinolone-resistant bacterial strains. | [Synthesis]
The synthesis of Lascufloxacin hydrochloride can follow the route below
 | [References]
[1] In Vitro Activities and Spectrum of the Novel Fluoroquinolone Lascufloxacin (KRP-AM1977) DOI:10.1128/AAC.00120-17 |
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