ChemicalBook--->CAS DataBase List--->1433996-83-8

1433996-83-8

1433996-83-8 Structure

1433996-83-8 Structure
IdentificationBack Directory
[Name]

Ald-Ph-PEG5-t-butyl ester
[CAS]

1433996-83-8
[Synonyms]

Ald-Ph-PEG5-Boc
DF-PEG5-CH2CH2COOtBu
ALD-PH-PEG5-CH2CH2COOTBU
Ald-Ph-PEG5-t-butyl ester
Ald-Phenyl-PEG5-t-butyl ester
[Molecular Formula]

C22H34O8
[MDL Number]

MFCD24539463
[MOL File]

1433996-83-8.mol
[Molecular Weight]

426.5
Chemical PropertiesBack Directory
[Boiling point ]

521.3±50.0 °C(Predicted)
[density ]

1.107±0.06 g/cm3(Predicted)
Hazard InformationBack Directory
[Description]

Ald-Ph-PEG5-t-butyl ester is a pEG reagent with a benzaldehyde group that is reactive with aminooxy (NH2O) containing molecules, The t-butyl ester is an acid labile protecting group.
[Uses]

Ald-Ph-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs; Alkyl/ether
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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