ChemicalBook--->CAS DataBase List--->143492-38-0

143492-38-0

143492-38-0 Structure

143492-38-0 Structure
IdentificationBack Directory
[Name]

D-ERYTHRO-MAPP
[CAS]

143492-38-0
[Synonyms]

D-ERYTHRO-MAPP
L-erythro MAPP
MAPP, D-ERYTHRO
(1S,2R)-D-ERYTHRO-2-(N-MYRISTOYLAMINO)-1-PHENYL-1-PROPANOL
N-[(1R,2S)-2-HYDROXY-1-METHYL-2-PHENYLETHYL]-TETRADECANAMIDE
Tetradecanamide, N-[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]-
[Molecular Formula]

C23H39NO2
[MDL Number]

MFCD01076527
[MOL File]

143492-38-0.mol
[Molecular Weight]

361.56
Chemical PropertiesBack Directory
[Boiling point ]

536.7±43.0 °C(Predicted)
[density ]

0.965±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 20 mg/ml; DMSO: .1 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2) (1:2): .5 mg/ml
[form ]

White solid.
[pka]

13.70±0.20(Predicted)
[color ]

White to off-white
[InChI]

1S/C23H39NO2/c1-3-4-5-6-7-8-9-10-11-12-16-19-22(25)24-20(2)23(26)21-17-14-13-15-18-21/h13-15,17-18,20,23,26H,3-12,16,19H2,1-2H3,(H,24,25)/t20-,23-/m1/s1
[InChIKey]

YLAZEWZHIRBZDA-NFBKMPQASA-N
Safety DataBack Directory
[WGK Germany ]

WGK 1
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

N-[(1R,2S)-2-Hydroxy-1-methyl-2-phenylethyl]-tetradecanamide is a ceramide analog. It is an inhibitor of ceramidase.
[Definition]

ChEBI: N-[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]tetradecanamide is an alkylbenzene.
[Biological Activity]

Cell permeable: yes''Primary Target
Alkaline ceramidase''Product does not compete with ATP.''Reversible: no''Target IC50: 1-5 μM for alkaline ceramidase versus >500 μM for acid ceramidase
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