| Identification | Back Directory | [Name]
NCGC00247743 | [CAS]
1435192-04-3 | [Synonyms]
NCGC00247743
NCGC-00247743,NCGC00247743
Benzamide, N-[6-(dimethylamino)hexyl]-3-(8-hydroxy-6-quinolinyl)- | [Molecular Formula]
C24H29N3O2 | [MOL File]
1435192-04-3.mol | [Molecular Weight]
391.51 |
| Chemical Properties | Back Directory | [Boiling point ]
613.8±55.0 °C(Predicted) | [density ]
1.139±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 62.5 mg/mL (159.64 mM);Water : < 0.1 mg/mL (insoluble) | [form ]
Solid | [pka]
4.81±0.40(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
NCGC00247743 is a histone lysine demethylase KDM4 inhibitor. | [IC 50]
KDM4 | [References]
[1] Duan L, et al. KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes. Chem Biol. 2015 Sep 17;22(9):1185-96. DOI:10.1016/j.chembiol.2015.08.007 |
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