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143558-00-3

143558-00-3 Structure

143558-00-3 Structure
IdentificationBack Directory
[Name]

rocuronium
[CAS]

143558-00-3
[Synonyms]

rocuronium
1-[17β-(Acetyloxy)-3α-hydroxy-2β-morpholino-5α-androstan-16β-yl]-1-(2-propenyl)pyrrolidinium
1-[(2beta,3alpha,5alpha,16beta,17beta)-17-(Acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)pyrrolidinium
[Molecular Formula]

C32H53N2O4
[MDL Number]

MFCD07364046
[MOL File]

143558-00-3.mol
[Molecular Weight]

529.781
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO
[form ]

Powder
Hazard InformationBack Directory
[Uses]

Rocuronium (Org-9426) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia.
[Definition]

ChEBI: A 5alpha-androstane compound having 3alpha-hydroxy-, 17beta-acetoxy-, 2beta-morpholino- and 16beta-N-allyllyrrolidinium substituents.
[storage]

Store at -20°C
[References]

[1] Konishi J, Suzuki T, Kondo Y, Baba M, Ogawa S. Rocuronium and sugammadex used effectively for electroconvulsive therapy in a patient with Brugada syndrome. J ECT. 2012 Jun;28(2):e21-2. DOI:10.1097/YCT.0b013e31824b74f5
[2] Zhang Y, Xiang Y, Liu J. Prevention of pain on injection of rocuronium: a comparison of lidocaine with different doses of parecoxib. J Clin Anesth. 2012 Jul 2. DOI:10.1016/j.jclinane.2011.12.006
[3] Suzuki T, Nameki K, Shimizu H, Shimizu Y, Nakamura R, Ogawa S. Efficacy of rocuronium and sugammadex in a patient with dermatomyositis. Br J Anaesth. 2012 Apr;108(4):703. DOI:10.1093/bja/aes087
[4] Illodo Miramontes G, Doniz Campos M, Filgueira Garrido P, Vázquez Martínez A. Rocuronium used in rapid sequence intubation and reversal with sugammadex in a patient with myasthenia gravis.Rev Esp Anestesiol Reanim. 2011 Dec;58(10):626-7. PMID:22263415
[5] García Sánchez JI, Martínez Hurtado ED, Tordecilla Echenique YY, Santa-Ursula TJ. Rocuronium used after sugammadex.Rev Esp Anestesiol Reanim. 2011 Dec;58(10):620-1. PMID:22263410
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