| Identification | Back Directory | [Name]
1-METHOXY-9ALPHA, 11ALPHA, 15S-TRIHYDROXYPROSTA-5Z, 13E-DIENE | [CAS]
143656-18-2 | [Synonyms]
AGN191129
PGF2α-OMe
PGF2ALPHA-OME
UNII-NK1168QB5T
Prostaglandin F2α alcohol methyl ether
Prostaglandin F2α Alcohol methyl ether
PROSTAGLANDIN F2ALPHA ALCOHOL METHYL ETHER
1-METHOXY-9ALPHA, 11ALPHA, 15S-TRIHYDROXYPROSTA-5Z, 13E-DIENE
(1S,3R,4R,5R)-4-[(E,3S)-3-hydroxyoct-1-enyl]-5-[(Z)-7-methoxyhept-2-enyl]cyclopentane-1,3-diol | [Molecular Formula]
C21H38O4 | [MDL Number]
MFCD00913925 | [MOL File]
143656-18-2.mol | [Molecular Weight]
354.52 |
| Chemical Properties | Back Directory | [Boiling point ]
482.1±45.0 °C(Predicted) | [density ]
1.056±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 7 mg/ml; DMSO: 15 mg/ml; Ethanol: 9 mg/ml; PBS (7.2): 0.16 mg/ml | [pka]
14.59±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Prostaglandin F2α alcohol methyl ether is an alcohol methyl ether G protein-coupled receptor. Prostaglandin F2α is also a luteinizing hormone in sheep and may be a nociceptive mediator in the spinal cord[1][2][3]. | [Definition]
ChEBI: PGF2alpha methyl ether is an aliphatic alcohol. | [storage]
Store at -20°C | [References]
[1] Richie-Jannetta R, et al. Structural determinants for calcium mobilization by prostaglandin E2 and prostaglandin F2alpha glyceryl esters in RAW 264.7 cells and H1819 cells. Prostaglandins Other Lipid Mediat. 2010 Jun;92(1-4):19-24. DOI:10.1016/j.prostaglandins.2010.01.003
[2] Woodward DF, et al. Recent progress in prostaglandin F2α ethanolamide (prostamide F2α) research and therapeutics. Pharmacol Rev. 2013 Jul 26;65(4):1135-47. DOI:10.1124/pr.112.007088
[3] McCracken J A, et al. Prostaglandin F2α identified as a luteolytic hormone in sheep[J]. Nature New Biology, 1972, 238(83): 129-134. |
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