| Identification | Back Directory | [Name]
CC401 HCl | [CAS]
1438391-30-0 | [Synonyms]
CC-401 (hydrochloride)
CC-401 dihydrochloride >=95% (HPLC)
CC 401 HYDROCHLORIDE; CC401 HYDROCHLORIDE; CC401 HCL
3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole hydrochloride (1:1) | [Molecular Formula]
C22H25ClN6O | [MDL Number]
MFCD21364765 | [MOL File]
1438391-30-0.mol | [Molecular Weight]
424.927 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 100 mg/mL (235.33 mM; Need ultrasonic) | [form ]
White powder. | [color ]
White to off-white | [Water Solubility ]
H2O: 10mg/mL, clear |
| Hazard Information | Back Directory | [Uses]
CC-401 inhibits c-JUN N-terminal kinases (JNKs) by binding to its ATP-binding site. JNKs belong to the MAP kinase family and respond to stress signals such as heat, cytokines, and osmotic shock. | [Biological Activity]
CC-401 is a cell penetrantpotent and selective c-Jun N terminal kinase (JNK) inhibitor th at blocks JNK signaling in the r at obstructed kidney and inhibits renal fibrosis in the unilateral ureteral obstruction model. CC-401 in combination with chemotherapy exhibits synergism in colon cancer cell lines. |
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| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
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