| Identification | Back Directory | [Name]
Benzoic acid, 3-[4-[(4-carboxy-3-methoxy-2,5,6-trimethylphenoxy)carbonyl]-3-methoxy-2,5,6-trimethylphenoxy]-4,6-dihydroxy-2,5-dimethyl-, 1-[4-[(4-carboxy-3-methoxy-2,5,6-trimethylphenoxy)carbonyl]-3-methoxy-2,5,6-trimethylphenyl] ester | [CAS]
144118-26-3 | [Synonyms]
Thielocin B1
Thielocin-B1
Benzoic acid, 3-[4-[(4-carboxy-3-methoxy-2,5,6-trimethylphenoxy)carbonyl]-3-methoxy-2,5,6-trimethylphenoxy]-4,6-dihydroxy-2,5-dimethyl-, 1-[4-[(4-carboxy-3-methoxy-2,5,6-trimethylphenoxy)carbonyl]-3-methoxy-2,5,6-trimethylphenyl] ester | [Molecular Formula]
C53H58O17 | [MOL File]
144118-26-3.mol | [Molecular Weight]
967.03 |
| Hazard Information | Back Directory | [Description]
Thielocin B1 is a protein-protein interaction inhibitor of PAC3 homodimer. Thielocin B1 was isolated as a novel phospholipase A2 inhibitor from the fermentation broth of Thielavia terricola RF-143. | [Uses]
Thielocin B1 is a protein-protein interaction inhibitor of PAC3 homodimer[1]. | [References]
[1] Doi T, et, al. Total synthesis and characterization of thielocin B1 as a protein–protein interaction inhibitor of PAC3 homodimer. Chem. Sci., 5(5), 1860-1868. |
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