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Lanopepden mesylate (GSK 1322322 mesylate) is a peptide deformase (PDF) inhibitor. Lanopepden mesylate has antibacterial activity by inhibiting the activity of PDF, preventing the correct synthesis of bacterial proteins. Lanopepden mesylate mainly targets Gram-positive bacteria. Lanopepden mesylate can be used in the study of acute bacterial skin and skin structural infections[1]. | [References]
[1] Lee H Y, et al. Identification of novel aminopiperidine derivatives for antibacterial activity against Gram-positive bacteria[J]. Bioorganic & Medicinal Chemistry Letters, 2016, 26(13): 3148-3152. DOI:10.1016/j.bmcl.2016.04.086 |
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