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144208-62-8

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144208-62-8 Structure

144208-62-8 Structure
IdentificationBack Directory
[Name]

Toluene-4-sulfonic acid 2-(2-benzyloxycarbonylamino-ethoxy)-ethyl ester
[CAS]

144208-62-8
[Synonyms]

2-(2-(((benzyloxy)carbonyl)amino)ethoxy)ethyl 4-methylbenzenesulfonate
Toluene-4-sulfonic acid 2-(2-benzyloxycarbonylamino-ethoxy)-ethyl ester
[Molecular Formula]

C19H23NO6S
[MDL Number]

MFCD29059964
[MOL File]

144208-62-8.mol
[Molecular Weight]

393.45
Chemical PropertiesBack Directory
[Boiling point ]

576.3±50.0 °C(Predicted)
[density ]

1.246±0.06 g/cm3(Predicted)
[form ]

Viscous Liquid
[pka]

11.98±0.46(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Description]

2-(2-(((Benzyloxy)carbonyl)amino)ethoxy)ethyl 4-methylbenzenesulfonate is a PEG linker containing a tosyl group and benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
[Uses]

OTs-PEG1-NHCbz is a PEG linker containing a tosyl group and benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of the compound in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
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