Identification | Back Directory | [Name]
MM-401 | [CAS]
1442106-10-6 | [Synonyms]
MM-401 MM-401(MM 401 N-[(3R,9S,12R)-9-[3-(diaminomethylideneamino)propyl]-6-ethyl-12-methyl-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacyclohexadec-12-yl]-2-methylpropanamide | [Molecular Formula]
C29H46N8O5 | [MOL File]
1442106-10-6.mol | [Molecular Weight]
586.73 |
Hazard Information | Back Directory | [Uses]
MM-401 is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity (IC50 = 0.32 μM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia[1]. | [References]
[1] Fang Cao, et al. Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia. Mol Cell. 2014 Jan 23;53(2):247-61. DOI:10.1016/j.molcel.2013.12.001 |
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Company Name: |
Alabiotech Inc.
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Tel: |
001-619-354-5251 |
Website: |
www.alabiotech-e.com |
Company Name: |
InvivoChem
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Tel: |
13549236410 |
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https://www.invivochem.cn/ |
Company Name: |
hangzhoubaiyibiolog
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Tel: |
15658107580 |
Website: |
www.chemicalbook.com/showsupplierproductslist1389215/0.htm |
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