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144298-98-6

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144298-98-6 Structure

144298-98-6 Structure
IdentificationBack Directory
[Name]

Ch55-O-C3-NH2
[CAS]

144298-98-6
[Synonyms]

RAR ligand 1
Ch55-O-C3-NH2
[Molecular Formula]

C27H35NO4
[MOL File]

144298-98-6.mol
[Molecular Weight]

437.57
Chemical PropertiesBack Directory
[Boiling point ]

595.5±50.0 °C(Predicted)
[density ]

1.103±0.06 g/cm3(Predicted)
[pka]

3.31±0.36(Predicted)
Hazard InformationBack Directory
[Uses]

Ch55-O-C3-NH2 (RAR ligand 1) is a Ch 55-based ligand, which targets RAR. Ch55-O-C3-NH2 (RAR ligand 1) binds to cIAP1 ligand Bestatin via a linker to form SNIPER[1].
[References]

[1] Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176. DOI:10.1016/j.csbj.2019.01.006
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