| Identification | Back Directory | [Name]
4-Thiazolidinone, 5-[3-[2-[(2-methoxyphenyl)methoxy]phenyl]-2-propen-1-ylidene]-2-thioxo- | [CAS]
1443442-61-2 | [Synonyms]
CG707
CG-707
CG 707
4-Thiazolidinone, 5-[3-[2-[(2-methoxyphenyl)methoxy]phenyl]-2-propen-1-ylidene]-2-thioxo- | [Molecular Formula]
C20H17NO3S2 | [MOL File]
1443442-61-2.mol | [Molecular Weight]
383.48 |
| Hazard Information | Back Directory | [Description]
CG-707 is a PRL-3 inhibitor that acts by blocking the migration and invasion of metastatic cancer cells. | [Uses]
CG-707 inhibits phosphatase of regenerating liver-3 (PRL-3) enzymatic activity with an IC50 value of 0.8 μM. CG-707 inhibits the migration and invasion of PRL-3 overexpressing colon cancer cells[1]. | [References]
[1] Min G, et al. Rhodanine-based PRL-3 inhibitors blocked the migration and invasion of metastatic cancer cells. Bioorg Med Chem Lett. 2013 Jul 1;23(13):3769-74. DOI:10.1016/j.bmcl.2013.04.092 |
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