| Identification | Back Directory | [Name]
obscurolide A1 | [CAS]
144397-99-9 | [Synonyms]
obscurolide A1
4-[[Tetrahydro-2-(3-hydroxy-1-butenyl)-5-oxo-3-furanyl]amino]-benzoic acid
Benzoic acid, 4-[[tetrahydro-2-(3-hydroxy-1-butenyl)-5-oxo-3-furanyl]amino]- (9CI) | [Molecular Formula]
C15H17NO5 | [MDL Number]
MFCD14635422 | [MOL File]
144397-99-9.mol | [Molecular Weight]
291.3 |
| Hazard Information | Back Directory | [Description]
Obscurolide A1 is a natural butyrolactone isolated from S. viridochromogenes.1 It inhibits calcium/calmodulin-dependent phosphodiesterase from bovine brain, presumably PDE1 (IC50 = 15 mM).1 | [Uses]
Obscurolide A1 is a Phosphodiesterase (PDE) inhibitor (IC50=8 mM) that can be obtained from Streptomyces viridochromogenes culture. Obscurolide A1 has the potential to study neurological and inflammatory diseases[1]. | [Definition]
ChEBI: Obscurolide A1 is an aminobenzoic acid. | [storage]
Store at -20°C | [References]
1. Hoff, H., Drautz, H., Fiedler, H.P., et al. Metabolic products of microorganisms. 261. Obscurolides, a novel class of phosphodiesterase inhibitors from streptomyces. I. Production, isolation, structural elucidation and biological activity of obscurolides A1 to A4 J. Antibiot. (Tokyo) 45(7),1096-1107(1992). |
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| Company Name: |
Lynnchem
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| Telephone: |
86-(0)29-85992781 17792393971 |
| Website: |
http://www.lynnchem.com/ |
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