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144459-70-1

144459-70-1 Structure

144459-70-1 Structure
IdentificationBack Directory
[Name]

Rofleponide
[CAS]

144459-70-1
[Synonyms]

Rofleponide
Unii-R9iq7gvl3e
Rofleponide [inn]
Pregn-4-ene-3,20-dione, 16,17-[(1R)-butylidenebis(oxy)]-6,9-difluoro-11,21-dihydroxy-, (6α,11β,16α)-
[Molecular Formula]

C25H34F2O6
[MDL Number]

MFCD00914391
[MOL File]

144459-70-1.mol
[Molecular Weight]

468.534
Chemical PropertiesBack Directory
[Boiling point ]

597.0±50.0 °C(Predicted)
[density ]

1.32±0.1 g/cm3(Predicted)
[pka]

12.87±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

Rofleponide is a synthetic glucocorticoid that has a high affinity for rat thymic glucocorticoid receptors and has high anti-inflammatory efficacy in experimental animal models[1].
[References]

[1] Thalén A, et al. Synthesis and structure elucidation of potential 6-oxygenated metabolites of (22R)-6α, 9α-difluoro-11β, 21-dihydroxy-16α, 17α-propylmethylenedioxypregn-4-ene-3, 20-dione, and related glucocorticosteroids[J]. Steroids, 2000, 65(1): 16-23. DOI:10.1016/s0039-128x(99)00080-x
Spectrum DetailBack Directory
[Spectrum Detail]

Rofleponide(144459-70-1)1HNMR
144459-70-1 suppliers list
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