ChemicalBook--->CAS DataBase List--->1445830-39-6

1445830-39-6

1445830-39-6 Structure

1445830-39-6 Structure
IdentificationBack Directory
[Name]

BAY524
[CAS]

1445830-39-6
[Synonyms]

[Molecular Formula]

C24H24F2N6O3
[MOL File]

1445830-39-6.mol
[Molecular Weight]

482.48
Chemical PropertiesBack Directory
[Boiling point ]

568.8±50.0 °C(Predicted)
[density ]

1.33±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 166.67 mg/mL (345.44 mM)
[form ]

Solid
[pka]

5.40±0.26(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Description]

BAY-524 is a Bub1 kinase inhibitor.
[Uses]

BAY-524 is a potent Bub1 kinase inhibitor. BAY-524 inhibits the recombinant catalytic domain of human Bub1 with an IC50 of 450 nM. BAY-524 can be used for the research of anti-cancer in combination with other agents[1].
[storage]

Store at -20°C
[References]

[1] Baron AP, et al. Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524. Elife. 2016 Feb 17;5. pii: e12187. DOI:10.7554/eLife.12187
Spectrum DetailBack Directory
[Spectrum Detail]

BAY524(1445830-39-6)1HNMR
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