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1445993-41-8

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1445993-41-8 Structure

1445993-41-8 Structure
IdentificationBack Directory
[Name]

BRD4-IN-5
[CAS]

1445993-41-8
[Synonyms]

BRD4-IN-5
[Molecular Formula]

C25H21F2N3O4
[MOL File]

1445993-41-8.mol
[Molecular Weight]

465.45
Chemical PropertiesBack Directory
[Boiling point ]

635.8±55.0 °C(predicted)
[density ]

1.45±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

13.74±0.20(predicted)
Hazard InformationBack Directory
[Uses]

BRD4-IN-5 (example 51) is a BRD4 inhibitor. The Ki values of the two BRD4 domains BDI_K57-E168 and BDII_E352-M457 are 9.7 nM and 16.1 nM, respectively. BRD4-IN-5 can be used in cancer research[1].
[IC 50]

BDI_K57-E168: 9.7 nM (Ki); BDII_E352-M457: 16.1 nM (Ki)
[References]

[1] Le Wang, et al. Bromodomain inhibitors. International Publication Date. 2013.04.07.
1445993-41-8 suppliers list
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Website: https://www.targetmol.cn/
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