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144606-93-9

144606-93-9 Structure

144606-93-9 Structure
IdentificationBack Directory
[Name]

Triphosphoric acid, P-[[4-(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-2-cyclopenten-1-yl]methyl] ester, (1R-cis)- (9CI)
[CAS]

144606-93-9
[Synonyms]

LCBVTP
L-CBVTP
L CBVTP
(+)-Carbovir triphosphate
Triphosphoric acid, P-[[4-(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-2-cyclopenten-1-yl]methyl] ester, (1R-cis)- (9CI)
[Molecular Formula]

C11H16N5O11P3
[MOL File]

144606-93-9.mol
[Molecular Weight]

487.19
Chemical PropertiesBack Directory
[Boiling point ]

890.5±75.0 °C(Predicted)
[density ]

2.37±0.1 g/cm3(Predicted)
[pka]

0.81±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

(+)-Carbovir triphosphate is an enantiomer of Carbovir triphosphate (HY-131607). (+)-Carbovir triphosphate is an inhibitor and substrate of HIV reverse transcriptase[1].
[References]

[1] Miller WH, et al. Phosphorylation of carbovir enantiomers by cellular enzymes determines the stereoselectivity of antiviral activity. J Biol Chem. 1992 Oct 15;267(29):21220-4. PMID:1383219
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