| Identification | Back Directory | [Name]
2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindoline-5-carbaldehyde | [CAS]
1447701-63-4 | [Synonyms]
2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindole-5-carbaldehyde
2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindoline-5-carbaldehyde
1H-Isoindole-5-carboxaldehyde, 2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo- | [Molecular Formula]
C14H10N2O5 | [MDL Number]
MFCD34549483 | [MOL File]
1447701-63-4.mol | [Molecular Weight]
286.24 |
| Hazard Information | Back Directory | [Uses]
Thalidomide-5-carbaldehyde is a Thalidomide analogue with an aldehyde. Thalidomide recruiits E3 ligase for the ubiquitinylation and subsequent proteolysis of target proteins. The aldehyde is highly reactive towards amine nucleophiles through reductive amination among other reactions. |
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