| Identification | Back Directory | [Name]
(2S,3S)-3-[N-(Quinoxaline-2-carbonyl)-L-asparaginyl]amino-2-hydroxy-4- phenylbutanoyl-L-proline, tert-butylamide | [CAS]
144779-91-9 | [Synonyms]
R87366
R-87366
R 87366
(2S,3S)-3-[N-(Quinoxaline-2-carbonyl)-L-asparaginyl]amino-2-hydroxy-4- phenylbutanoyl-L-proline, tert-butylamide
L-Prolinamide, N2-(2-quinoxalinylcarbonyl)-L-asparaginyl-(αS,βS)-β-amino-α-hydroxybenzenebutanoyl-N-(1,1-dimethylethyl)- (9CI) | [Molecular Formula]
C32H39N7O6 | [MDL Number]
MFCD00953510 | [MOL File]
144779-91-9.mol | [Molecular Weight]
617.7 |
| Chemical Properties | Back Directory | [Boiling point ]
1055.458±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.311±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
10.009±0.46(predicted) |
| Hazard Information | Back Directory | [Description]
R 87366 is a water-soluble HIV protease inhibitor. | [Uses]
R-87366 is a water-soluble human immunodeficiency virus (HIV) protease inhibitor. R-87366 has potent inhibitory for HIV protease with a Ki value of 11 nM. R-87366 can be used for the research of anti-human immunodeficiency virus (HIV)[1]. | [References]
[1] T Komai, et al. In vitro and ex vivo anti-human immunodeficiency virus (HIV) activities of a new water-soluble HIV protease inhibitor, R-87366, containing (2S,3S)-3-amino-2-hydroxy-4-phenylbutanoic acid. Biol Pharm Bull. 1997 Feb;20(2):175-80. DOI:10.1248/bpb.20.175 |
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