ChemicalBook--->CAS DataBase List--->1447824-16-9

1447824-16-9

1447824-16-9 Structure

1447824-16-9 Structure
IdentificationBack Directory
[Name]

Acetyl Hexapeptide-37
[CAS]

1447824-16-9
[Synonyms]

Diffuporine
Acetyl Hexapeptide-37
[EINECS(EC#)]

-0
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
[Sequence]

Ac-Ser-Pro-Ala-Gly-Gly-Pro-NH2
[Cosmetics Ingredients Functions]

SKIN CONDITIONING
Hazard InformationBack Directory
[Description]

Acetyl hexapeptide-37 is a synthetic peptide composed of the amino acids alanine, proline, serine and glycine. This peptide works with the water channels (known as aquaporins) in skin's surface layers, helping to provide adequate, balanced hydration between skin's layers, a process which alleviates signs of dry, dehydrated skin.
[Definition]

acetyl hexapeptide-37 is the product obtained by the acetylation of hexapeptide-37.
[benefits]

Acetyl Hexapeptide-37can improve activity of fibroblast in dermalmesoderm,replenish the collagen, maintain thefirmness and elasticity, used in early anti-agingand morsturizing products.
[Biological Functions]

Boosts Aquaporin-3 which promotes inner hydration mechanisms and water movement from the basal layer of epidermis and to the stratum corneum, rejuvenating the skin by improving barrier function, collagen I synthesis and cellular proliferation.
[Mode of action]

Acetyl hexapeptide-37 improves skin moisturisation via an enhanced aquaporin 3 (AQP3) expression. As this membrane protein is involved in water transport through the different tissue layers, an increased concentration of it in the skin improves the water flux from the basal layer of the epidermis to the stratum corneum. Moreover, acetyl hexapeptide-37 improves the barrier function and increases collagen I synthesis and keratinocyte proliferation.
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