ChemicalBook--->CAS DataBase List--->144874-49-7

144874-49-7

144874-49-7 Structure

144874-49-7 Structure
IdentificationBack Directory
[Name]

3',5'-Di-O-acetyl-2'-deoxy-5,N3-di methyluridine
[CAS]

144874-49-7
[Synonyms]

Thymidine, 3-methyl-, 3',5'-diacetate (9CI)
3’,5’-Di-O-acetyl-2’-deoxy-5,N3-dimethyluridine
3',5'-Di-O-acetyl-2'-deoxy-5,N3-di methyluridine
[Molecular Formula]

C15H20N2O7
[MDL Number]

MFCD31814047
[MOL File]

144874-49-7.mol
[Molecular Weight]

340.33
Chemical PropertiesBack Directory
[Boiling point ]

449.5±55.0 °C(Predicted)
[density ]

1.34±0.1 g/cm3(Predicted)
[pka]

-2.02±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

3’,5’-Di-O-acetyl-2’-deoxy-5,N3-dimethyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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