| Identification | Back Directory | [Name]
CS 722 | [CAS]
144886-17-9 | [Synonyms]
CS 722
4-chloro-2-[(2R)-2-hydroxy-3-morpholin-4-ylpropyl]-5-phenyl-1,2-oxazol-3-one | [Molecular Formula]
C16H19ClN2O4.ClH | [MOL File]
144886-17-9.mol | [Molecular Weight]
375.25 |
| Hazard Information | Back Directory | [Description]
CS 722 is a centrally acting muscle relaxant. CS-722 exerts its muscle relaxant action by affecting both the supraspinal structure and the spinal cord. | [Uses]
CS-722 is a centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex[1]. CS-722 inhibits spontaneous inhibitory postsynaptic currents and excitatory postsynaptic currents in hippocampal cultures probably by an inhibition of both sodium and calcium currents[1][2]. | [References]
[1] Marszalec W, et al. The effects of the muscle relaxant, CS-722, on synaptic activity of cultured neurones. Br J Pharmacol. 1996 Sep;119(1):126-32. DOI:10.1111/j.1476-5381.1996.tb15685.x
[2] Tanabe M, et al. Preferential enhancement of inhibitory synaptic transmission by CS-722 in the ventral horn neurons of neonatal rat spinal cord. Eur J Pharmacol. 1996 Oct 17;313(3):187-9. DOI:10.1016/0014-2999(96)00634-6 |
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