| Identification | Back Directory | [Name]
2-chloro-N-(3-((1,1-dioxidobenzo[d]isothiazol-3-yl)amino)phenyl)acetamide | [CAS]
1449236-96-7 | [Synonyms]
2-Chloro-N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)amino]phenyl}acetamide
2-chloro-N-(3-((1,1-dioxidobenzo[d]isothiazol-3-yl)amino)phenyl)acetamide
Acetamide, 2-chloro-N-[3-[(1,1-dioxido-1,2-benzisothiazol-3-yl)amino]phenyl]- | [Molecular Formula]
C15H12ClN3O3S | [MDL Number]
MFCD28963957 | [MOL File]
1449236-96-7.mol | [Molecular Weight]
349.79 |
| Chemical Properties | Back Directory | [density ]
1.52±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : ≥ 42 mg/mL (120.07 mM) | [form ]
Solid | [pka]
12.40±0.70(Predicted) | [color ]
White to gray |
| Hazard Information | Back Directory | [Uses]
NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively. | [References]
[1] Magnaghi P, et al. Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death. Nat Chem Biol. 2013 Sep;9(9):548-56. DOI:10.1038/nchembio.1313 |
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Musechem
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+1-800-259-7612 |
| Website: |
www.musechem.com |
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