| Identification | Back Directory | [Name]
BIBN 140 | [CAS]
145301-79-7 | [Synonyms]
BIBN 140
Pentanamide, N-[3-[1-[2-(10,11-dihydro-11-oxo-5H-dibenzo[b,e][1,4]diazepin-5-yl)-2-oxoethyl]-4-piperidinyl]propyl]-N-ethyl-2,2-dimethyl- | [Molecular Formula]
C32H44N4O3 | [MOL File]
145301-79-7.mol | [Molecular Weight]
532.72 |
| Hazard Information | Back Directory | [Description]
Bibn 140 is a highly selective M2 antagonist with applications to Alzheimer's disease and other cognitive disorders. | [Uses]
Bibn 140 is a pyridine derivative substituted with a benzene ring, which has high affinity (Ki: 12 nM) and selectivity for M2 mAChR receptors over M1 receptors[1]. | [References]
[1] THERAPEUTIC POTENTIAL OF CNS-ACTIVE M 2 ANTAGONISTS: NOVEL STRUCTURES AND PHARMACOLOGY |
|
|