| Identification | Back Directory | [Name]
4-[1-Chloro-2-(methylamino)ethyl]phenyl Acetate Hydrochloride | [CAS]
14593-25-0 | [Synonyms]
4-(1-Chloro-2-(methylamino)
phenyl acetate hydrochloride
Glucocorticoid Receptor Modulator, CpdA
4-[1-CHLORO-2-(METHYLAMINO)ETHYL]PHENYL ACETATE HCL
4-[1-Chloro-2-(methylamino)ethyl]phenyl Acetate Hydrochloride
Glucocorticoid Receptor Modulator, CpdA - CAS 14593-25-0 - Calbiochem | [Molecular Formula]
C11H15Cl2NO2 | [MOL File]
14593-25-0.mol | [Molecular Weight]
264.148 |
| Chemical Properties | Back Directory | [Melting point ]
177-179 °C | [storage temp. ]
= -70C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
White solid | [color ]
Pale to Light Brown |
| Hazard Information | Back Directory | [Uses]
Glucocorticoid receptor activator 1 (compound A) is a phenyl aziridine precursor and an activator of the glucocorticoid receptor (GR). Glucocorticoid receptor activator 1 down-modulates TNF-induced pro-inflammatory gene expression by activating GR and can be utilized in inflammation research[1]. | [storage]
Store at -20°C | [References]
[1] De Bosscher K, et al. A fully dissociated compound of plant origin for inflammatory gene repression. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15827-32. DOI:10.1073/pnas.0505554102 |
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