| Identification | Back Directory | [Name]
GJ103 | [CAS]
1459687-89-8 | [Synonyms]
GJ103
2-(4-(3-methoxyphenyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid
Acetic acid, 2-[[4-(3-methoxyphenyl)-5-(2-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]- | [Molecular Formula]
C16H14N4O3S | [MOL File]
1459687-89-8.mol | [Molecular Weight]
342.37 |
| Chemical Properties | Back Directory | [Boiling point ]
630.1±65.0 °C(Predicted) | [density ]
1.40±0.1 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [solubility ]
DMSO: 68 mg/mL (198.62 mM);Ethanol: Insoluble | [pka]
2.92±0.10(Predicted) | [Water Solubility ]
Water: Insoluble |
| Hazard Information | Back Directory | [Uses]
GJ-103 can induce read through of nonsense mutations in ATM gene. | [in vivo]
GJ103 (10-30 μM; 4 days) induces ATM kinase activity in AT153LA cells with a homozygous TGA mutation and a homozygous TAA mutation[1].
GJ103 does not show obvious cytotoxicity in A-T cells at concentration as high as 300 μM[1]. | [storage]
Store at -20°C |
|
| Company Name: |
Twochem Co.Ltd.
|
| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
|