| Identification | Back Directory | [Name]
dactylocycline D | [CAS]
146064-00-8 | [Synonyms]
dactylocycline D
2-Naphthacenecarboxamide, 6-[[3-[(acetyloxy)amino]-2,3,6-trideoxy-3-C-methyl-4-O-methyl-α-L-arabino-hexopyranosyl]oxy]-7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,4a,10,12,12a-pentahydroxy-8-methoxy-6-methyl-1,11-dioxo-, [4R-(4α,4aα,5aα,6α,12aα)]- (9CI) | [Molecular Formula]
C33H42ClN3O14 | [MOL File]
146064-00-8.mol | [Molecular Weight]
740.16 |
| Hazard Information | Back Directory | [Description]
Dactylocyclines is novel tetracycline derivatives produced by a Dactylosporangium sp. A screen for antibiotics with activity against tetracycline-resistant microorganisms has led to the isolation of Dactylosporangium sp. (ATCC 53693), a producer of several novel tetracycline derivatives. The major fermentation products, dactylocyclines A and B, were purified and MIC values determined against tetracycline-resistant and tetracycline-sensitive Gram-positive bacteria. The dactylocyclines represent the first naturally occurring tetracycline C2 amides which lack cross resistance with tetracycline. | [Uses]
Dactylocycline D is an active compound. | [References]
[1] Dactylocyclines, novel tetracycline derivatives produced by a Dactylosporangium sp. II. Structure elucidation |
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