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146144-48-1

146144-48-1 Structure

146144-48-1 Structure
IdentificationBack Directory
[Name]

(3R)-3-[[2-[(3R)-2-oxo-3-[2-(4-piperidyl)ethyl]-1-piperidyl]acetyl]amino]butanoic acid
[CAS]

146144-48-1
[Synonyms]

L734
L-734
L 734
L734217
L-734217
L 734217
(3R)-3-[[2-[(3R)-2-oxo-3-[2-(4-piperidyl)ethyl]-1-piperidyl]acetyl]amino]butanoic acid
Butanoic acid, 3-[[2-[(3R)-2-oxo-3-[2-(4-piperidinyl)ethyl]-1-piperidinyl]acetyl]amino]-, (3R)-
[Molecular Formula]

C18H31N3O4
[MOL File]

146144-48-1.mol
[Molecular Weight]

353.46
Chemical PropertiesBack Directory
[Boiling point ]

629.3±40.0 °C(Predicted)
[density ]

1.123±0.06 g/cm3(Predicted)
[pka]

4.27±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

L-734217 is an orally active and potent fibrinogen receptor antagonist and an antithrombotic agent. L-734217 is excreted largely by the renal route and partly into the bile in dogs. L-734217 is promising for research of thrombotic disorders[1].
[References]

[1] Prueksaritanont T, et al. Effects of pentobarbital on pharmacokinetics and pharmacodynamics of a potent fibrinogen receptor antagonist, L-734,217, in dogs. Biopharm Drug Dispos. 1997 Nov;18(8):649-63. DOI:10.1002/(sici)1099-081x(199711)18:8<649::aid-bdd51>3.0.co;2-t
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