ChemicalBook--->CAS DataBase List--->1462949-64-9

1462949-64-9

1462949-64-9 Structure

1462949-64-9 Structure
IdentificationBack Directory
[Name]

(7-(5-fluoro-2-methoxyphenyl)-2-((2-isopropoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)thieno[3,2-d]pyrimidin-6-yl)methanol
[CAS]

1462949-64-9
[Synonyms]

EOS-61938
SAR-348830;SAR 348830
ALK kinase inhibitor-1
SAR348830;SAR-348830;SAR 348830
(7-(5-fluoro-2-methoxyphenyl)-2-((2-isopropoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)thieno[3,2-d]pyrimidin-6-yl)methanol
Thieno[3,2-d]pyrimidine-6-methanol, 7-(5-fluoro-2-methoxyphenyl)-2-[[2-(1-methylethoxy)-4-(4-methyl-1-piperazinyl)phenyl]amino]-
kinase,ALK tyrosine kinase receptor,Anaplastic lymphoma kinase,lymphoma,Anaplastic lymphoma kinase (ALK),inhibit,Inhibitor,Cluster of differentiation 246,ALK kinase inhibitor 1,ALK kinase inhibitor-1,ALK kinase inhibitor1,anaplastic,ALK,CD246
[EINECS(EC#)]

604-604-1
[Molecular Formula]

C28H32FN5O3S
[MDL Number]

MFCD29924784
[MOL File]

1462949-64-9.mol
[Molecular Weight]

537.65
Chemical PropertiesBack Directory
[Boiling point ]

735.9±70.0 °C(Predicted)
[density ]

1.300±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 100 mg/mL (185.99 mM; Need ultrasonic)
[form ]

Solid
[pka]

12.88±0.10(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

ALK kinase inhibitor-1 is an anaplastic lymphoma kinase (ALK) inhibitor extracted from patent US20130261106A1 compound I-202[1].
[References]

[1] Carry JC, et, al. Novel thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof. US20130261106A1.
Spectrum DetailBack Directory
[Spectrum Detail]

(7-(5-fluoro-2-methoxyphenyl)-2-((2-isopropoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)thieno[3,2-d]pyrimidin-6-yl)methanol(1462949-64-9)1HNMR
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