| Identification | Back Directory | [Name]
1H-Imidazole, 2-(3,4-dihydro-5-methoxy-1H-2-benzopyran-1-yl)-4,5-dihydro-, sulfate (1:1) | [CAS]
1465908-73-9 | [Synonyms]
Tasipimidine sulfate
1H-Imidazole, 2-(3,4-dihydro-5-methoxy-1H-2-benzopyran-1-yl)-4,5-dihydro-, sulfate (1:1) | [Molecular Formula]
C13H18N2O6S | [MOL File]
1465908-73-9.mol | [Molecular Weight]
330.36 |
| Chemical Properties | Back Directory | [storage temp. ]
4°C, away from moisture | [solubility ]
DMSO : 125 mg/mL (378.38 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Tasipimidine sulfate is an orally active and selective α2A-adrenoceptor agonist with a pEC50 of 7.57 against human α2A-adrenoceptor. Tasipimidine sulfate can be used for situational anxiety and fear research[1]. | [IC 50]
human α2A-adrenoceptor: 7.57 (pEC50); rodent α2D-adrenoceptor: 6.56 (pEC50); human α2C-adrenoceptor: 6.29 (pEC50); human α2B-adrenoceptor: 6.00 (pEC50) | [storage]
4°C, away from moisture | [References]
[1] Lehtim?ki J, et al. Tasipimidine-the pharmacological profile of a novel orally active selective α2A-adrenoceptor agonist. Eur J Pharmacol. 2022 May 15;923:174949. DOI:10.1016/j.ejphar.2022.174949 |
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