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146949-21-5

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146949-21-5 Structure

146949-21-5 Structure
IdentificationBack Directory
[Name]

SCH 48973
[CAS]

146949-21-5
[Synonyms]

V074
v-073
SCH 48973
Pocapavir
V-073 Sch-48973
Pocapavir(SCH-48973
POCAPAVIR;SCH-48973; SCH48973; SCH 48973; V074; V 073; V-073; POCAPAVIR
Benzene, 1-[(2-chloro-4-methoxyphenoxy)methyl]-4-[(2,6-dichlorophenoxy)methyl]-
[Molecular Formula]

C21H17Cl3O3
[MDL Number]

MFCD00950032
[MOL File]

146949-21-5.mol
[Molecular Weight]

423.72
Chemical PropertiesBack Directory
[Boiling point ]

541.4±45.0 °C(Predicted)
[density ]

1.329±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO:100.0(Max Conc. mg/mL);236.0(Max Conc. mM)
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections[1].
[References]

[1] Collett MS, et al. Antiviral Activity of Pocapavir in a Randomized, Blinded, Placebo-Controlled Human Oral Poliovirus Vaccine Challenge Model. J Infect Dis. 2017 Feb 1;215(3):335-343. DOI:10.1093/infdis/jiw542
Spectrum DetailBack Directory
[Spectrum Detail]

SCH 48973(146949-21-5)1HNMR
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