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147076-36-6

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147076-36-6 Structure

147076-36-6 Structure
IdentificationBack Directory
[Name]

Laflunimus
[CAS]

147076-36-6
[Synonyms]

Laflunimus
LCBOKWGFIPORJD-QBFSEMIESA-N
2-Propenamide, 2-cyano-3-cyclopropyl-3-hydroxy-N-[3-methyl-4-(trifluoromethyl)phenyl]-, (2Z)-
[Molecular Formula]

C15H13F3N2O2
[MDL Number]

MFCD28502173
[MOL File]

147076-36-6.mol
[Molecular Weight]

310.27
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[color ]

Yellow to khaki
Hazard InformationBack Directory
[Uses]

Laflunimus-d4 is labeled Laflunimus (L168510) which is used to treat neuropathic pain and the neuropathic pain syndromes.
[in vivo]

HR325 (50 mg/kg; p.o.; days 14-18 after being injected with SRBC) inhibits the secondary anti-sheep red blood cell (SRBC) antibody response with ID50 values of 38 mg/kg[1].

Animal Model:Male CD-1 mice (20-24 g)[1]
Dosage:50 mg/kg
Administration:Oral; days 14-18 after being injected with SRBC
Result:The level of circulating anti-SRBC IgG in this model was inhibited dose relatedly by orally administered HR325.
[storage]

Store at -20°C
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