| Identification | Back Directory | [Name]
(S)-Tenofovir | [CAS]
147127-19-3 | [Synonyms]
(S)-TDF
(S)-PMPA
(S)-GS 1278
(S)-Tenofovir
TAF Impurity L
Tenofovir alafenamide-23
Tenofovir Disoproxil Impurity 26
(S)-9-(2-Phosphonomethoxypropyl)adenine
[(2S)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid
(S)-(1-(6-aMino-9H-purin-9-yl)propan-2-yloxy)Methylphosphonic acid
(S)-[[[1-(6-Amino-9H-purin-9-yl)-2-propyl]oxy]methyl]phosphonic Acid
3-O-BENZYL-4-(HYDROXYMETHYL-1,2-O-ISOPROPYLIDENE)--D-ERYTHROPENTOFURANOSE
Phosphonic acid,P-[[(1S)-2-(6-aMino
-9H-purin-9-yl)-1-Methylethoxy]Methyl]-
Tenofovir impurity 45/(S)-(((1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic acid | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C9H14N5O4P | [MDL Number]
MFCD21604708 | [MOL File]
147127-19-3.mol | [Molecular Weight]
287.21 |
| Chemical Properties | Back Directory | [Melting point ]
>260°C (dec.) | [Boiling point ]
616.1±65.0 °C(Predicted) | [density ]
1.79±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
Solid | [pka]
2.36±0.10(Predicted) | [color ]
White to Off-White | [Optical Rotation]
Consistent with structure | [InChI]
InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m0/s1 | [InChIKey]
SGOIRFVFHAKUTI-LURJTMIESA-N | [SMILES]
P(CO[C@@H](C)CN1C2C(N=C1)=C(N)N=CN=2)(=O)(O)O |
| Hazard Information | Back Directory | [Uses]
(S)-Tenofovir is an S-enatiomeric derivative of Tenofovir (T018500). (S)-Tenofovir displays virucidal activity against herpes, visna virus and retrovirus. The S enantiomer of Tenofovir (T018500) is less effective against HIV than their (R)-enantiomeric counterparts. | [storage]
Store at -20°C |
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