| Identification | Back Directory | [Name]
β-Amyloid (1-9) | [CAS]
147529-30-4 | [Synonyms]
β-Amyloid 1-9
β-Amyloid (1-9)
β-Amyloid (1-9) USP/EP/BP | [Molecular Formula]
C42H60N14O17 | [MDL Number]
MFCD09841879 | [MOL File]
147529-30-4.mol | [Molecular Weight]
1033.02 |
| Chemical Properties | Back Directory | [density ]
1.60±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
3.21±0.10(Predicted) | [Sequence]
Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly |
| Hazard Information | Back Directory | [Uses]
β-Amyloid (1-9), an N-terminal fragment of beta amyloid, consists of amino acid residues 1 to 9. β-Amyloid (1-9) contains a B cell epitope, but it does not include T cell epitopes. Omission of residues 1 to 9 from the full-length Alzheimer'sβ-Amyloid peptide 1 to 40 does not prevent the peptide from forming amyloid fibrils or eliminate fibril polymorphism [1][2]. | [References]
[1] Zamora E, et al. Papillomavirus-like particles are an effective platform for amyloid-beta immunization in rabbitsand transgenic mice. J Immunol. 2006 Aug 15;177(4):2662-2670. DOI:10.4049/jimmunol.177.4.2662
[2] Paravastu AK, et al. Polymorphic fibril formation by residues 10-40 of the Alzheimer's beta-amyloid peptide. Biophys J. 2006 Jun 15;90(12):4618-29. DOI:10.1529/biophysj.105.076927 |
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