ChemicalBook--->CAS DataBase List--->147658-54-6

147658-54-6

147658-54-6 Structure

147658-54-6 Structure
IdentificationBack Directory
[Name]

H-ARG-ARG-TRP-CYS-TYR-ARG-LYS-CYS-TYR-LYS-GLY-TYR-CYS-TYR-ARG-LYS-CYS-ARG-NH2
[CAS]

147658-54-6
[Synonyms]

T22
T140
(TYR5,12,LYS7)-POLYPHEMUSIN II
POLYPHEMUSIN II-DERIVED PEPTIDE
(TYR5'12,LYS7)-POLYPHEMUSIN II (T22)
[TYR5,12, LYS7]-POLYPHEMUSIN II (T22)
H-ARG-ARG-2-NAL-CYS-TYR-ARG-LYS-D-LYS-PRO-TYR-ARG-CIT-CYS-ARG-OH
ARG-ARG-TRP-CYS-TYR-ARG-LYS-CYS-TYR-LYS-GLY-TYR-CYS-TYR-ARG-LYS-CYS-ARG-NH2
H-ARG-ARG-TRP-CYS-TYR-ARG-LYS-CYS-TYR-LYS-GLY-TYR-CYS-TYR-ARG-LYS-CYS-ARG-NH2
ARG-ARG-TRP-CYS-TYR-ARG-LYS-CYS-TYR-LYS-GLY-TYR-CYS-TYR-ARG-LYS-CYS-ARG-NH2 (DISULFIDE BRIDGE: CYS4- CYS17, CYS8-CYS13)
Arg-Arg-Trp-Cys-Tyr-Arg-Lys-Cys-Tyr-Lys-Gly-Tyr-Cys-Tyr-Arg-Lys-Cys-Arg-NH2 (Disulfide bridges Cys4-Cys17 and Cys8-Cys13)
Arg-Arg-Trp-Cys-Tyr-Arg-Lys-Cys-Tyr-Lys-Gly-Tyr-Cys-Tyr-Arg-Lys-Cys-Arg-NH2(Disulfide bridge: Cys4 and Cys17/Cys8 and Cys13)
L-Argininamide, L-arginyl-L-arginyl-L-tryptophyl-L-cysteinyl-L-tyrosyl-L-arginyl-L-lysyl-L-cysteinyl-L-tyrosyl-L-lysylglycyl-L-tyrosyl-L-cysteinyl-L-tyrosyl-L-arginyl-L-lysyl-L-cysteinyl-, cyclic (4→17),(8→13)-bis(disulfide)
[Molecular Formula]

C109H164N38O22S4
[MDL Number]

MFCD00677792
[MOL File]

147658-54-6.mol
[Molecular Weight]

2487
Chemical PropertiesBack Directory
[density ]

1.55±0.1 g/cm3(Predicted)
[storage temp. ]

-15°C
Hazard InformationBack Directory
[Uses]

T-22 (polyphemusin II with [Tyr5,12,Lys7]) is a new synthetic peptide that fights HIV, with an EC50 of 0.008 μg/mL and a CC50 of 54 μg/mL. T22 promotes plant height, photosynthesis, total chlorophyll content, and gas exchange in tomatoes, and it can resist CMV[1][2].
[References]

[1] Masao Masuda, et al. A novel anti-HIV synthetic peptide, T-22 ([Tyr5,12,Lys7]-polyphemusin II). Biochemical and Biophysical Research Communications. Volume 189, Issue 2, 15 December 1992, Pages 845-850. DOI:10.1016/0006-291x(92)92280-b
[2] Antonella Vitti, et al. Trichoderma harzianum T-22 Induces Systemic Resistance in Tomato Infected by Cucumber mosaic virus. Front Plant Sci. 2016 Oct 10:7:1520. DOI:10.3389/fpls.2016.01520
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