| Identification | Back Directory | [Name]
GAT107 | [CAS]
1476807-74-5 | [Synonyms]
GAT107
3H-Cyclopenta[c]quinoline-8-sulfonamide, 4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-, (3aR,4S,9bS)- | [Molecular Formula]
C18H17BrN2O2S | [MOL File]
1476807-74-5.mol | [Molecular Weight]
405.31 |
| Hazard Information | Back Directory | [Uses]
GAT107 (compound 1b) is a potent α7 nAChR ago-PAMs (positive allosteric modulators)[1]. | [References]
[1] Thakur GA, et al. Expeditious synthesis, enantiomeric resolution, and enantiomer functional characterization of (4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide (4BP-TQS): an allosteric agonist-positive allosteric modulator of α7 nicotinic acetylcholine receptors. J Med Chem. 2013 Nov 14;56(21):8943-7. DOI:10.1021/jm401267t |
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